Which statement accurately describes the role of iron-sulfur clusters in metabolism and their sensitivity to oxidative stress?

• A. They are stable under oxidative stress.
• B. They store iron and sulfur for later use but do not participate in redox.
• C. They function only in chloroplasts.
• D. Iron-sulfur clusters participate in electron transfer and are highly sensitive to oxidative stress, leading to impaired function.

Answer: (D)