Which shuttle transfers electrons to FAD in mitochondrial glycerol-3-phosphate dehydrogenase?

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Multiple Choice

Which shuttle transfers electrons to FAD in mitochondrial glycerol-3-phosphate dehydrogenase?

Explanation:
Glycerol-3-phosphate shuttle is the pathway that transfers electrons to FAD. In this shuttle, cytosolic NADH reduces DHAP to glycerol-3-phosphate, which then diffuses into the mitochondrion where mitochondrial glycerol-3-phosphate dehydrogenase oxidizes glycerol-3-phosphate back to DHAP and reduces FAD to FADH2. The FADH2 then donates electrons to ubiquinone (CoQ) in the electron transport chain. This differs from the malate-aspartate shuttle, which transfers electrons to NAD+ in the matrix (as NADH equivalents). So the shuttle that delivers electrons to FAD is the glycerol-3-phosphate shuttle.

Glycerol-3-phosphate shuttle is the pathway that transfers electrons to FAD. In this shuttle, cytosolic NADH reduces DHAP to glycerol-3-phosphate, which then diffuses into the mitochondrion where mitochondrial glycerol-3-phosphate dehydrogenase oxidizes glycerol-3-phosphate back to DHAP and reduces FAD to FADH2. The FADH2 then donates electrons to ubiquinone (CoQ) in the electron transport chain. This differs from the malate-aspartate shuttle, which transfers electrons to NAD+ in the matrix (as NADH equivalents). So the shuttle that delivers electrons to FAD is the glycerol-3-phosphate shuttle.

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