Which lipoprotein delivers cholesterol to peripheral tissues?

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Multiple Choice

Which lipoprotein delivers cholesterol to peripheral tissues?

LDL is the lipoprotein responsible for delivering cholesterol to peripheral tissues. It carries cholesterol esters and uses apolipoprotein B-100 to bind LDL receptors on many cell types. Once an LDL particle binds its receptor, cells take it up by receptor-mediated endocytosis, and the cholesterol esters are released for use in membrane synthesis, steroid production, or other needs. This receptor-mediated delivery makes LDL the primary vehicle for supplying cholesterol to most tissues. In contrast, HDL acts to shuttle excess cholesterol back to the liver (reverse cholesterol transport), chylomicrons mainly bring dietary triglycerides (and some cholesterol) to tissues with remnants largely returned to the liver, and VLDL primarily delivers hepatic triglycerides to tissues and is eventually converted to LDL.

LDL is the lipoprotein responsible for delivering cholesterol to peripheral tissues. It carries cholesterol esters and uses apolipoprotein B-100 to bind LDL receptors on many cell types. Once an LDL particle binds its receptor, cells take it up by receptor-mediated endocytosis, and the cholesterol esters are released for use in membrane synthesis, steroid production, or other needs. This receptor-mediated delivery makes LDL the primary vehicle for supplying cholesterol to most tissues. In contrast, HDL acts to shuttle excess cholesterol back to the liver (reverse cholesterol transport), chylomicrons mainly bring dietary triglycerides (and some cholesterol) to tissues with remnants largely returned to the liver, and VLDL primarily delivers hepatic triglycerides to tissues and is eventually converted to LDL.

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