Where does the amino acid attach to the tRNA?

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Study for the Biochemistry Module 6 Exam. Study with flashcards and multiple choice questions; each question includes hints and explanations. Gear up to ace your test!

Multiple Choice

Where does the amino acid attach to the tRNA?

Explanation:
The amino acid is attached at the 3' end of the tRNA, specifically to the 3' hydroxyl of the terminal adenosine (the A76) in the CCA tail. Aminoacyl-tRNA synthetases form an ester bond between the amino acid and this 3' OH, creating aminoacyl-tRNA ready for incorporation into protein. The anticodon loop is the site for codon recognition, not for attachment. The 5' end and the middle portion of the tRNA are not where the amino acid bonding occurs.

The amino acid is attached at the 3' end of the tRNA, specifically to the 3' hydroxyl of the terminal adenosine (the A76) in the CCA tail. Aminoacyl-tRNA synthetases form an ester bond between the amino acid and this 3' OH, creating aminoacyl-tRNA ready for incorporation into protein. The anticodon loop is the site for codon recognition, not for attachment. The 5' end and the middle portion of the tRNA are not where the amino acid bonding occurs.

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